AnthelMax ®

Praziquantel/ Pyrantel tablet
For veterinary use only.
Category: Broad spectrum combination anthelmintic
Form: Oral tablet
Target Animal: Cats
Compound: Each tablet contains 18.2 mg praziquantel and 72.6 mg pyrantel (equivalent to 209.27 mg pyrantel pamoate).
Indication: To eliminate tapeworms (Dipylidium Caninum, Taenia taeniaeformis), hookworms (Ancylostoma tubaeforme), and large roundworms (Toxocara Cati) in cats and kittens.
Mode of Action:
Praziquantel: Abruptly gets absorbed from parasite’s body surface, imposing severe damage upon parasite’s membrane. Also, by affecting cations exchange especially Calcium, parasite faces tetanic and paralytic contractions.
Pyrantel: Acts as a Cholinergic agonists and by stimulating Cholinergic Nicotinic receptors, Pyrantel enables paralysis and eliminates parasites via digestive system.
Pharmacokinetics:
Praziquantel: Once administered orally, it is absorbed completely via intestines and gets distributed throughout all the organs. In liver Praziquantel metabolizes inactively and secretes into bile. Approximately, more than 95% of the administered dose is excreted in 24 hours. A maximum quantity of Plasma density is created up to 2.5 hours after drug administration.
The Pamoate salt present in Pyrantel has a low solubility in water, therefore, reducing its absorption via digestive system and enhancing the probability of reaching into large intestine, affecting all parasites present in that area. Once absorbed, Pyrantel Pamoate fully and rapidly metabolizes with inactive metabolics and quickly excretes via urine.
Cautions: Must be kept out of reach of children. Consult your veterinarian before administering medication to a sick or pregnant cat.
Dosage and Administration:

 
Side effects: Although not all adverse reactions are reported, transient ataxia has been reported following the administration of Anthelmax® tablets for cats and kittens.
Preservation: Kept in a dry place and in room temperature (below 30° C).
Packing: A paperbox containing a blister of 4 tablets.
IVO Manufacturing License NO: 99-139-A.P
Manufacturing Date:
Expiry Date:
Serial No:
Manufactured by Damyaran Arak Pharmaceutical CO
Saveh- Iran