Products
DAMYARANARAK
Clindamycin 75 mg
For veterinary use only.
Category: A broad spectrum semi- synthesis Lincosamide antibiotic.
Form: Oral tablet. Compound: Each tablet contains 75 mg Clindamycin (Hydrochloride salt).
Target Animal: Dog. Indication: To treat dermal infections such as superficial abscesses and wounds created from Staphylococcus Aureus and Staphylococcus Intermedius, wounds and deep abscesses created from Bacteroides Fragilis, Fusobacterium Necrophorum and Clostridium Perfringes; treating dental infections and Osteomyelitis.
Mode of action: Clindamycin is a bacteriostatic lincosamide antimicrobial that is active against a broad spectrum of pathogenic aerobic and anaerobic bacteria. It inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit.
Pharmacokinetics: Clindamycin chloride salt is rapidly absorbed from the gastrointestinal tract wall after oral administration. The maximum serum concentration of the drug is achieved one and a quarter hours after oral administration, and the elimination half-life of the drug in dogs is an average of 5 hours. Extensive studies on the metabolism and excretion of clindamycin hydrochloride have shown that the drug is excreted unchanged along with its bioactive and non-bioactive metabolites in urine and feces.
Dosage and Administration: – 5/5- 33 mg per kg bodyweight once every 12 hours for cases of dermal wounds, abscesses, and dental infections. Treatment to be continued up to maximum 28 days. – 11-33 mg per kg bodyweight once every 12 hours for cases of Osteomyelitis. Treatment to be continued up to maximum 28 days. Contraindication: Not to be used for animals that experience hypersensitivity when consuming Clindamycin or Lincomycin.
Not to be prescribed for animals like rabbit, hamster, Indian piglet, horse and ruminants.
Cautions: Keep out of reach of children. The functionality of kidney and liver as well as blood cells’ count must continuously be monitored if treatment period is longer than a month. This drug must be prescribed cautiously for critical cases of renal and liver problems. The concurrent prescription of Clindamycin with Neuromuscular blocker drugs must be done cautiously due to Clindamycin’s Neuromuscular blocking effects.
Side Effects: There have been rare instances of diarrhea and vomiting reported.
Preservation: Keep in a dry place away from direct light and at room temperature (below 30°C).
Packing: Boxes of 50, 100 and 200 tablets (Blisters of 10)/ polyethylene containers 50, 100 and 200 tablets.